.Pharmacolibrary.Drugs.B_BloodAndBloodFormingOrgans.B03B_VitaminB12AndFolicAcid.B03BA03_Hydroxocobalamin.Hydroxocobalamin .Pharmacolibrary.Drugs.B_BloodAndBloodFormingOrgans.B03B_VitaminB12AndFolicAcid.B03BA03_Hydroxocobalamin.Hydroxocobalamin| name: | Hydroxocobalamin |
| ATC code: | B03BA03 | route: | intravenous |
| n-compartments | 2 |
Hydroxocobalamin is a form of vitamin B12 used in the treatment of vitamin B12 deficiency and as an antidote for cyanide poisoning. It is administered intravenously, especially in emergency medicine for cyanide poisoning. Hydroxocobalamin is approved and widely used today for these indications.
Pharmacokinetic parameters reported in healthy adult volunteers after intravenous administration.
Uhl, W, et al., & Kovar, A (2008). Changes in blood pressure after administration of hydroxocobalamin: relationship to changes in plasma cobalamins-(III) concentrations in healthy volunteers. Clinical toxicology (Philadelphia, Pa.) 46(6) 551–577. DOI:10.1080/15563650701829763 PUBMED:https://pubmed.ncbi.nlm.nih.gov/18584369