.Pharmacolibrary.Drugs.B_BloodAndBloodFormingOrgans.B05A_BloodAndRelatedProducts.B05AA01_Albumin.Albumin

Information

Albumin is a major plasma protein produced by the liver, commonly used therapeutically as a plasma volume expander in the management of shock, burns, hypoalbuminemia, and other conditions associated with low blood volume or pressure. It is approved for clinical use and is listed on the WHO Model List of Essential Medicines.

Pharmacokinetics

Pharmacokinetic parameters for intravenous administration of human serum albumin in healthy adult subjects.

References

1. Weerink, MAS, et al., & Colin, P (2017). Clinical Pharmacokinetics and Pharmacodynamics of Dexmedetomidine. Clinical pharmacokinetics 56(8) 893–913. DOI:10.1007/s40262-017-0507-7 PUBMED:https://pubmed.ncbi.nlm.nih.gov/28105598

2. Sathe, AG, et al., & Othman, AA (2024). Population Pharmacokinetics of Sacituzumab Govitecan in Patients with Metastatic Triple-Negative Breast Cancer and Other Solid Tumors. Clinical pharmacokinetics 63(5) 669–681. DOI:10.1007/s40262-024-01366-3 PUBMED:https://pubmed.ncbi.nlm.nih.gov/38578394

3. Sime, FB, et al., & Roberts, JA (2019). Population pharmacokinetics of total and unbound concentrations of intravenous posaconazole in adult critically ill patients. Critical care (London, England) 23(1) 205–None. DOI:10.1186/s13054-019-2483-9 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31171022

Revisions

• 06/2025 initial generated model