.Pharmacolibrary.Drugs.B_BloodAndBloodFormingOrgans.B05B_IVSolutions.B05BA03_Carbohydrates.Carbohydrates

Information

Carbohydrates for parenteral nutrition (such as glucose and related solutions) are used as sources of energy and are typically administered intravenously to patients who cannot obtain nutrition via the oral or enteral route. These are commonly employed in hospital settings for patients requiring supportive care. While not a 'drug' in the traditional sense, intravenous carbohydrates (glucose/dextrose) remain a standard and essential component of parenteral nutrition and are widely approved and used in clinical medicine today.

Pharmacokinetics

Estimated pharmacokinetic parameters for intravenous infusion of glucose in healthy adult individuals. Published literature directly reporting compartmental pharmacokinetic values for this ATC category is limited; parameters are estimated based on reported ranges for intravenous 5% dextrose solutions in adults.

References

1. Daly, K, et al., & Shirazi-Beechey, SP (2012). Expression of sweet receptor components in equine small intestine: relevance to intestinal glucose transport. American journal of physiology. Regulatory, integrative and comparative physiology 303(2) R199–R208. DOI:10.1152/ajpregu.00031.2012 PUBMED:https://pubmed.ncbi.nlm.nih.gov/22552794

2. el-Mougi, M, et al., & Pierce, NF (1996). Efficacy of standard glucose-based and reduced-osmolarity maltodextrin-based oral rehydration solutions: effect of sugar malabsorption. Bulletin of the World Health Organization 74(5) 471–477. PUBMED:https://pubmed.ncbi.nlm.nih.gov/9002327

3. Molla, AM, et al., & Khatun, M (1986). Does oral rehydration therapy alter food consumption and absorption of nutrients in children with cholera?. The Journal of tropical medicine and hygiene 89(3) 113–117. PUBMED:https://pubmed.ncbi.nlm.nih.gov/3773023

Revisions

• 06/2025 initial generated model