.Pharmacolibrary.Drugs.B_BloodAndBloodFormingOrgans.B05B_IVSolutions.B05BB02_ElectrolytesWithCarbohyd.ElectrolytesWithCarbohyd

Information

name:ElectrolytesWithCarbohydrates
ATC code:B05BB02
route:oral
n-compartments1

Electrolytes with carbohydrates are used as oral or intravenous rehydration solutions for the treatment and prevention of dehydration due to diarrhea, vomiting, or other conditions causing fluid loss. They commonly contain sodium, potassium, chloride, bicarbonate (or citrate), and glucose or other simple carbohydrates to facilitate absorption via the sodium-glucose transporter. These products are widely used and accepted in clinical practice and are recommended by the WHO for oral rehydration therapy.

Pharmacokinetics

No dedicated pharmacokinetic modeling studies are available for the composite product 'electrolytes with carbohydrates' as a drug entity in healthy volunteers or specific patient groups. Absorption and disposition of oral rehydration solutions are governed by physiological processes of intestinal uptake and renal excretion.

References

  1. Holtug, K, et al., & Skadhauge, E (1996). Experimental studies of intestinal ion and water transport. Scandinavian journal of gastroenterology. Supplement 216 95–110. DOI:10.3109/00365529609094565 PUBMED:https://pubmed.ncbi.nlm.nih.gov/8726283

  2. Sze, DM, & Chan, GC (2009). Supplements for immune enhancement in hematologic malignancies. Hematology. American Society of Hematology. Education Program None 313–319. DOI:10.1182/asheducation-2009.1.313 PUBMED:https://pubmed.ncbi.nlm.nih.gov/20008216

  3. Feng, Y, et al., & Wu, H (2024). Microalgae polyphosphate nanoparticles deliver bioavailable calcium against phytate antagonism: Ex vivo and in vivo studies. Food research international (Ottawa, Ont.) 186 114321–None. DOI:10.1016/j.foodres.2024.114321 PUBMED:https://pubmed.ncbi.nlm.nih.gov/38729691

Revisions


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