.Pharmacolibrary.Drugs.B_BloodAndBloodFormingOrgans.B05C_IrrigatingSolutions.B05CB04_SodiumBicarbonate.SodiumBicarbonate

Information

name:SodiumBicarbonate
ATC code:B05CB04
route:intravenous
n-compartments1

Sodium bicarbonate is an alkalinizing agent used primarily to treat metabolic acidosis, severe renal impairment, certain drug intoxications, and to alkalinize urine. It is also used in emergency medicine for the management of hyperkalemia and some types of poisoning. Sodium bicarbonate is approved and widely used in clinical practice, typically administered intravenously in acute care settings.

Pharmacokinetics

Estimated pharmacokinetic parameters for adult patients; no specific publication reporting detailed pharmacokinetic modeling available. Mostly used intravenously in hospital and emergency settings.

References

  1. Abumanhal-Masarweh, H, et al., & Schroeder, A (2019). Sodium bicarbonate nanoparticles modulate the tumor pH and enhance the cellular uptake of doxorubicin. Journal of controlled release : official journal of the Controlled Release Society 296 1–13. DOI:10.1016/j.jconrel.2019.01.004 PUBMED:https://pubmed.ncbi.nlm.nih.gov/30615983

  2. Tarning, J, et al., & Jittamala, P (2024). Safety and pharmacokinetic properties of a new formulation of parenteral artesunate in healthy Thai volunteers. Malaria journal 23(1) 296–None. DOI:10.1186/s12936-024-05085-9 PUBMED:https://pubmed.ncbi.nlm.nih.gov/39363296

  3. Levitskaia, TG, et al., & Thrall, KD (2010). Biomaterials for the decorporation of (85)Sr in the rat. Health physics 99(3) 394–400. DOI:10.1097/HP.0b013e3181c4717d PUBMED:https://pubmed.ncbi.nlm.nih.gov/20699703

Revisions


Generated at 2025-07-21T18:21:10Z by OpenModelicaOpenModelica 1.25.1 using GenerateDoc.mos