name: | Hemin |
ATC code: | B06AB01 | route: | intravenous |
n-compartments | 1 |
Hemin is an iron-containing metalloporphyrin used primarily for the treatment of acute intermittent porphyria and related acute porphyrias. It is administered as a heme replacement to suppress the hepatic production of porphyrin precursors. Hemin is currently approved for medical use by major regulatory agencies such as FDA.
Pharmacokinetic parameters estimated for adult patients with acute intermittent porphyria, following intravenous administration. Published clinical PK data for hemin are limited; the following values are estimated based on sparse literature and product information.