.Pharmacolibrary.Drugs.C_CardiovascularSystem.C01B_AntiarrhythmicsClassIAndIii.C01BA08_Prajmaline.Prajmaline_1

Information

Prajmaline is an antiarrhythmic drug of the class Ia, developed from the plant alkaloid ajmaline. It is used to treat certain cardiac arrhythmias, such as ventricular and supraventricular tachycardias. Prajmaline is not widely approved or used in clinical practice today, with usage mainly reported in some European countries and limited global distribution.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adults (male and female) following oral administration.

References

1. Breuel, HP, et al., & Bondy, S (1991). Pharmacokinetics and relative bioavailability of prajmalium bitartrate after single oral dosing. Arzneimittel-Forschung 41(12) 1222–1225. PUBMED:https://pubmed.ncbi.nlm.nih.gov/1815520

Revisions

• 06/2025 initial generated model