.Pharmacolibrary.Drugs.C_CardiovascularSystem.C01B_AntiarrhythmicsClassIAndIii.C01BA71_QuinidineCombinationsWit.QuinidineCombinationsWit .Pharmacolibrary.Drugs.C_CardiovascularSystem.C01B_AntiarrhythmicsClassIAndIii.C01BA71_QuinidineCombinationsWit.QuinidineCombinationsWit| name: | QuinidineCombinationsWithPsycholeptics |
| ATC code: | C01BA71 | route: | oral |
| n-compartments | 2 |
Quinidine is an antiarrhythmic drug used primarily for the treatment of atrial and ventricular arrhythmias. It is also known for its role as a CYP2D6 inhibitor. Combinations with psycholeptics (such as antipsychotics or tranquilizers) have been used historically for treatment-resistant psychiatric conditions involving comorbid cardiac issues, but are not widely used or approved in current practice due to safety concerns and availability of better alternatives.
Estimated pharmacokinetics for adult population receiving quinidine in combination with psycholeptics; values are based on quinidine monotherapy due to lack of published data for the combination.