.Pharmacolibrary.Drugs.C_CardiovascularSystem.C01B_AntiarrhythmicsClassIAndIii.C01BD04_Dofetilide.Dofetilide

Information

name:Dofetilide
ATC code:C01BD04
route:oral
n-compartments2

Dofetilide is a class III antiarrhythmic agent used for the maintenance of normal sinus rhythm in patients with atrial fibrillation or atrial flutter. It is approved for clinical use and acts primarily by blocking the cardiac potassium channel to prolong repolarization.

Pharmacokinetics

Pharmacokinetics reported for healthy adult volunteers after oral administration.

References

  1. Dokoumetzidis, A, & Aarons, L (2005). Propagation of population pharmacokinetic information using a Bayesian approach: comparison with meta-analysis. Journal of pharmacokinetics and pharmacodynamics 32(3-4) 401–418. DOI:10.1007/s10928-005-0048-9 PUBMED:https://pubmed.ncbi.nlm.nih.gov/16320100

Revisions

Generated at 2025-07-21T18:21:10Z by OpenModelicaOpenModelica 1.25.1 using GenerateDoc.mos