name: | Indometacin_1 | |
ATC code: | C01EB03_1 | route: | intravenous |
compartments: | 2 | |
dosage: | 50 | mg |
volume of distribution: | 0.35 | L |
clearance: | 0.08 | L/h/kg |
other parameters in model implementation |
Indometacin (indomethacin) is a widely used NSAID for pain relief and anti-inflammatory effects, approved and used for various musculoskeletal disorders.
Pharmacokinetics after intravenous administration in healthy adults.
Smyth, JM, et al., & McElnay, JC (2004). Intravenous indometacin in preterm infants with symptomatic patent ductus arteriosus. A population pharmacokinetic study. British journal of clinical pharmacology 58(3) 249–258. DOI:10.1111/j.1365-2125.2004.02139.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/15327584