.Pharmacolibrary.Drugs.C_CardiovascularSystem.C02A_AntiadrenergicAgentsCentrallyActing.C02AC04_Tolonidine.Tolonidine .Pharmacolibrary.Drugs.C_CardiovascularSystem.C02A_AntiadrenergicAgentsCentrallyActing.C02AC04_Tolonidine.Tolonidine| name: | Tolonidine | |
| ATC code: | C02AC04 | route: | oral |
| compartments: | 1 | |
| dosage: | 20 | mg |
| volume of distribution: | 2 | L |
| clearance: | 12 | L/h |
| other parameters in model implementation | ||
Tolonidine is an antihypertensive drug classified as an imidazoline derivative and centrally acting alpha-2 adrenergic agonist. It was formerly used for the treatment of high blood pressure but is not widely approved or used today and is considered obsolete in most countries.
No peer-reviewed human pharmacokinetic data for tolonidine could be identified. All values are estimated based on its chemical similarity to clonidine and general pharmacokinetic properties of centrally acting antihypertensives.