.Pharmacolibrary.Drugs.C_CardiovascularSystem.C02K_OtherAntihypertensives.C02KX03_Sitaxentan.Sitaxentan

Information

name:Sitaxentan
ATC code:C02KX03
route:oral
n-compartments2

Sitaxentan is an endothelin receptor antagonist developed for the treatment of pulmonary arterial hypertension (PAH). It selectively blocks the endothelin-A receptor. Sitaxentan was withdrawn globally due to liver toxicity concerns and is not currently approved or in clinical use.

Pharmacokinetics

Population pharmacokinetics reported for adult patients with pulmonary arterial hypertension after oral dosing.

References

    Revisions

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