name: | HydrochlorothiazideCombinations |
ATC code: | C03AX01 | route: | oral |
n-compartments | 1 |
Hydrochlorothiazide is a thiazide diuretic used in combination medicines to treat hypertension and edema. Its main role is to inhibit sodium reabsorption in the distal tubules of the kidney, promoting diuresis. These fixed-dose combinations are widely used, and the drug is approved and remains in current clinical practice.
Pharmacokinetic parameters relate to healthy adult subjects who received single oral doses of fixed-dose hydrochlorothiazide combination products.