.Pharmacolibrary.Drugs.C_CardiovascularSystem.C03A_LowCeilingDiureticsThiazides.C03AX01_HydrochlorothiazideCombi.HydrochlorothiazideCombi .Pharmacolibrary.Drugs.C_CardiovascularSystem.C03A_LowCeilingDiureticsThiazides.C03AX01_HydrochlorothiazideCombi.HydrochlorothiazideCombi| name: | HydrochlorothiazideCombinations | |
| ATC code: | C03AX01 | route: | oral |
| compartments: | 1 | |
| dosage: | 25 | mg |
| volume of distribution: | 19 | L |
| clearance: | 3.1 | L/hr |
| other parameters in model implementation | ||
Hydrochlorothiazide is a thiazide diuretic used in combination medicines to treat hypertension and edema. Its main role is to inhibit sodium reabsorption in the distal tubules of the kidney, promoting diuresis. These fixed-dose combinations are widely used, and the drug is approved and remains in current clinical practice.
Pharmacokinetic parameters relate to healthy adult subjects who received single oral doses of fixed-dose hydrochlorothiazide combination products.