.Pharmacolibrary.Drugs.C_CardiovascularSystem.C03C_HighCeilingDiuretics.C03CB02_BumetanideAndPotassium.BumetanideAndPotassium .Pharmacolibrary.Drugs.C_CardiovascularSystem.C03C_HighCeilingDiuretics.C03CB02_BumetanideAndPotassium.BumetanideAndPotassium| name: | BumetanideAndPotassium | |
| ATC code: | C03CB02 | |
| route: | oral | |
| compartments: | 1 | |
| dosage: | 1 | mg |
| volume of distribution: | 0.24 | L |
| clearance: | 108 | ml/min |
| other parameters in model implementation | ||
Bumetanide is a potent loop diuretic used primarily for the treatment of edema associated with congestive heart failure, liver cirrhosis, and renal disease, including nephrotic syndrome. Potassium is often co-administered to mitigate hypokalemia caused by bumetanide. This combination is used clinically where both diuretic and potassium supplementation are required, and bumetanide is an approved diuretic agent.
No published pharmacokinetic data specific to the bumetanide and potassium combination was found. Estimates are based on published data for bumetanide administered orally in adults with normal renal function.