.Pharmacolibrary.Drugs.C_CardiovascularSystem.C03C_HighCeilingDiuretics.C03CC02_TienilicAcid.TienilicAcid

Information

name:TienilicAcid
ATC code:C03CC02
route:oral
n-compartments1

Tienilic acid is a thiophene derivative classified as a loop diuretic, formerly used to treat edema and hypertension. It acts primarily as an inhibitor of the renal tubular reabsorption of sodium and chloride. Due to its severe hepatotoxicity, tienilic acid was withdrawn from the market in the early 1980s and is not currently approved for use.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers after oral administration.

References

    Revisions

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