.Pharmacolibrary.Drugs.C_CardiovascularSystem.C03E_DiureticsAndPotassiumSparingAgentsInCombination.C03EA13_BendroflumethiazideAndPo.BendroflumethiazideAndPo .Pharmacolibrary.Drugs.C_CardiovascularSystem.C03E_DiureticsAndPotassiumSparingAgentsInCombination.C03EA13_BendroflumethiazideAndPo.BendroflumethiazideAndPo| name: | BendroflumethiazideAndPotassiumSparingAgents |
| ATC code: | C03EA13 | route: | oral |
| n-compartments | 1 |
Bendroflumethiazide and potassium-sparing agents is a combination product used to treat hypertension and edema. Bendroflumethiazide is a thiazide diuretic that reduces sodium reabsorption in the kidney, while potassium-sparing agents such as amiloride or triamterene help to prevent hypokalemia. These combination products are clinically approved and commonly prescribed today to manage high blood pressure and fluid retention.
Estimated typical pharmacokinetic parameters for adults based on known properties of bendroflumethiazide and common potassium-sparing agents (e.g., amiloride or triamterene) in healthy subjects. No direct published population PK study for the combination product was found; parameters are based on individual agent literature and typical adult dosing.