.Pharmacolibrary.Drugs.C_CardiovascularSystem.C05A_AgentsForTreatmentOfHemorrhoidsAndAnalFissuresFo.C05AA04_Prednisolone.Prednisolone_1 .Pharmacolibrary.Drugs.C_CardiovascularSystem.C05A_AgentsForTreatmentOfHemorrhoidsAndAnalFissuresFo.C05AA04_Prednisolone.Prednisolone_1| name: | Prednisolone_1 |
| ATC code: | C05AA04_1 | route: | intravenous |
| n-compartments | 2 |
Prednisolone is a synthetic glucocorticoid used primarily as an anti-inflammatory and immunosuppressant. It is used in the treatment of various conditions such as allergic disorders, autoimmune diseases, and certain types of cancer. Prednisolone is widely approved and commonly used in clinical practice today.
Pharmacokinetics in adult patients following intravenous bolus administration.
Petersen, KB, et al., & Schmiegelow, K (2003). Population pharmacokinetics of prednisolone in children with acute lymphoblastic leukemia. Cancer chemotherapy and pharmacology 51(6) 465–473. DOI:10.1007/s00280-003-0602-3 PUBMED:https://pubmed.ncbi.nlm.nih.gov/12698270
Honoré, PM, et al., & Spapen, HD (2014). What do we know about steroids metabolism and 'PK/PD approach' in AKI and CKD especially while on RRT--current status in 2014. Blood purification 38(2) 154–157. DOI:10.1159/000368390 PUBMED:https://pubmed.ncbi.nlm.nih.gov/25471548
Hill, MR, et al., & Brenner, AM (1990). Monitoring glucocorticoid therapy: a pharmacokinetic approach. Clinical pharmacology and therapeutics 48(4) 390–398. DOI:10.1038/clpt.1990.167 PUBMED:https://pubmed.ncbi.nlm.nih.gov/2225699