.Pharmacolibrary.Drugs.C_CardiovascularSystem.C07A_BetaBlockingAgents.C07AB07_Bisoprolol.Bisoprolol

Information

name:Bisoprolol
ATC code:C07AB07
route:oral
n-compartments2

Bisoprolol is a cardioselective beta-1 adrenergic receptor blocker used for the treatment of arterial hypertension, chronic stable angina pectoris, and chronic heart failure. It is widely approved and used today for cardiovascular indications.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers after a single oral dose.

References

  1. Nikolic, VN, et al., & Milovanovic, JR (2018). Population Pharmacokinetic Analysis of Bisoprolol in Patients with Stable Coronary Artery Disease. European journal of drug metabolism and pharmacokinetics 43(1) 35–44. DOI:10.1007/s13318-017-0414-1 PUBMED:https://pubmed.ncbi.nlm.nih.gov/28577178

  2. Grevel, J, et al., & Whiting, B (1989). Population pharmacokinetic analysis of bisoprolol. Clinical pharmacokinetics 17(1) 53–63. DOI:10.2165/00003088-198917010-00005 PUBMED:https://pubmed.ncbi.nlm.nih.gov/2568209

  3. Hayes, PC, et al., & Williams, R (1987). Single oral dose pharmacokinetics of bisoprolol 10 mg in liver disease. European heart journal 8 Suppl M 23–29. DOI:10.1093/eurheartj/8.suppl_m.23 PUBMED:https://pubmed.ncbi.nlm.nih.gov/2897298

Revisions

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