.Pharmacolibrary.Drugs.C_CardiovascularSystem.C07C_BetaBlockingAgentsAndOtherDiuretics.C07CB02_MetoprololAndOtherDiuret.MetoprololAndOtherDiuret .Pharmacolibrary.Drugs.C_CardiovascularSystem.C07C_BetaBlockingAgentsAndOtherDiuretics.C07CB02_MetoprololAndOtherDiuret.MetoprololAndOtherDiuret| name: | MetoprololAndOtherDiuretics | |
| ATC code: | C07CB02 | route: | oral |
| compartments: | 1 | |
| dosage: | 100 | mg |
| volume of distribution: | 200 | L |
| clearance: | 60 | L/h |
| other parameters in model implementation | ||
Metoprolol and other diuretics (ATC code C07CB02) refers to combination therapies used in the management of hypertension and heart failure, where metoprolol (a selective beta-1 adrenergic blocker) is combined with one or more diuretics. These combinations provide antihypertensive and cardioprotective effects and remain approved for use today in various formulations.
No published pharmacokinetic models specifically for the fixed combination product 'metoprolol and other diuretics' (ATC C07CB02). The following parameters are estimated based on typical metoprolol and thiazide diuretic oral co-administration in adults with hypertension.