.Pharmacolibrary.Drugs.C_CardiovascularSystem.C08C_SelectiveCalciumChannelBlockersWithMainlyVascula.C08CA51_AmlodipineAndCelecoxib.AmlodipineAndCelecoxib .Pharmacolibrary.Drugs.C_CardiovascularSystem.C08C_SelectiveCalciumChannelBlockersWithMainlyVascula.C08CA51_AmlodipineAndCelecoxib.AmlodipineAndCelecoxib| name: | AmlodipineAndCelecoxib |
| ATC code: | C08CA51 | route: | oral |
| n-compartments | 2 |
Amlodipine and celecoxib is a combination drug consisting of amlodipine, a calcium channel blocker used for treating hypertension and angina, and celecoxib, a selective COX-2 inhibitor nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of pain and inflammatory conditions such as arthritis. This fixed-dose combination is not widely approved as a fixed together formulation but both drugs are used individually and occasionally in combination for cardiovascular patients requiring concomitant pain management.
Estimated pharmacokinetic parameters for typical healthy adult subjects assuming oral co-administration and typical doses based on known monotherapy pharmacokinetic data, as no published human PK model for the fixed combination exists.