.Pharmacolibrary.Drugs.C_CardiovascularSystem.C08C_SelectiveCalciumChannelBlockersWithMainlyVascula.C08CA55_NifedipineCombinations.NifedipineCombinations .Pharmacolibrary.Drugs.C_CardiovascularSystem.C08C_SelectiveCalciumChannelBlockersWithMainlyVascula.C08CA55_NifedipineCombinations.NifedipineCombinations| name: | NifedipineCombinations |
| ATC code: | C08CA55 | route: | oral |
| n-compartments | 2 |
Nifedipine is a dihydropyridine calcium channel blocker used to treat hypertension and angina pectoris. It works by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle cells, leading to vasodilation and decreased blood pressure. Combinations may be used clinically, typically alongside other antihypertensive or antianginal agents. Nifedipine-containing combinations are approved and currently used in clinical practice for cardiovascular conditions.
Estimated population pharmacokinetic parameters for oral nifedipine in healthy adult subjects, as there are no available published data specific for ATC code C08CA55 combinations. The values are based on well-established typical pharmacokinetics of nifedipine immediate-release administered orally.
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