.Pharmacolibrary.Drugs.C_CardiovascularSystem.C08D_SelectiveCalciumChannelBlockersWithDirectCardiac.C08DB01_Diltiazem.Diltiazem_1

Information

name:Diltiazem_1
ATC code:C08DB01_1
route:intravenous
n-compartments2

Diltiazem is a non-dihydropyridine calcium channel blocker (class IV antiarrhythmic) used to treat hypertension, angina pectoris, and arrhythmias. It is clinically approved and in use.

Pharmacokinetics

Pharmacokinetic parameters after intravenous administration in healthy adults.

References

  1. Abernethy, DR (1989). The pharmacokinetic profile of amlodipine. American heart journal 118(5 Pt 2) 1100–1103. DOI:10.1016/0002-8703(89)90834-x PUBMED:https://pubmed.ncbi.nlm.nih.gov/2530866

  2. Zhang, Y, et al., & Miao, L (2025). Exploring the comprehensive factors influencing tacrolimus pharmacokinetics in early renal transplant recipients: A population pharmacokinetic analysis. European journal of clinical pharmacology 81(5) 785–799. DOI:10.1007/s00228-025-03825-7 PUBMED:https://pubmed.ncbi.nlm.nih.gov/40126611

Revisions

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