.Pharmacolibrary.Drugs.C_CardiovascularSystem.C09A_AceInhibitorsPlain.C09AA05_Ramipril.Ramipril

Information

Ramipril is an angiotensin-converting enzyme (ACE) inhibitor used primarily for the treatment of hypertension, heart failure, and to reduce the risk of cardiovascular events in high-risk patients. It is an approved and widely used antihypertensive medication.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers after single oral dose administration.

References

1. He, YL (2012). Clinical pharmacokinetics and pharmacodynamics of vildagliptin. Clinical pharmacokinetics 51(3) 147–162. DOI:10.2165/11598080-000000000-00000 PUBMED:https://pubmed.ncbi.nlm.nih.gov/22339447

2. Russell, C, et al., & Mohammed, AR (2015). Paediatric drug development of ramipril: reformulation, in vitro and in vivo evaluation. Journal of drug targeting 23(9) 854–863. DOI:10.3109/1061186X.2015.1036275 PUBMED:https://pubmed.ncbi.nlm.nih.gov/25950602

3. Chatsiricharoenkul, S, et al., & Kongpatanakul, S (2011). Bioequivalence study of 10 mg ramipril tablets in healthy Thai volunteers. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 94(10) 1260–1266. PUBMED:https://pubmed.ncbi.nlm.nih.gov/22145513

Revisions

• 06/2025 initial generated model