.Pharmacolibrary.Drugs.C_CardiovascularSystem.C09A_AceInhibitorsPlain.C09AA07_Benazepril.Benazepril

Information

Benazepril is an angiotensin-converting enzyme (ACE) inhibitor used primarily for the treatment of hypertension and congestive heart failure. It is approved and widely used in clinical practice today, both alone and in combination with other antihypertensive agents.

Pharmacokinetics

Pharmacokinetic data reported after single oral dose administration of benazepril in healthy adult volunteers.

References

1. Gengo, FM, & Brady, E (1991). The pharmacokinetics of benazepril relative to other ACE inhibitors. Clinical cardiology 14(8 Suppl 4) IV44–IV55. DOI:10.1002/clc.4960141807 PUBMED:https://pubmed.ncbi.nlm.nih.gov/1893642

2. Ding, PY, et al., & Liao, W (2000). Does Chinese ethnicity affect the pharmacokinetics and pharmacodynamics of angiotensin-converting enzyme inhibitors?. Journal of human hypertension 14(3) 163–170. DOI:10.1038/sj.jhh.1000856 PUBMED:https://pubmed.ncbi.nlm.nih.gov/10694829

3. Kaiser, G, et al., & Holmes, IB (1990). The influence of hepatic cirrhosis on the pharmacokinetics of benazepril hydrochloride. Biopharmaceutics & drug disposition 11(9) 753–764. DOI:10.1002/bdd.2510110903 PUBMED:https://pubmed.ncbi.nlm.nih.gov/2271751

Revisions

• 06/2025 initial generated model