.Pharmacolibrary.Drugs.C_CardiovascularSystem.C09A_AceInhibitorsPlain.C09AA08_Cilazapril.Cilazapril

Information

Cilazapril is an angiotensin-converting enzyme (ACE) inhibitor used primarily for the treatment of hypertension and congestive heart failure. It is usually administered orally and works by preventing the conversion of angiotensin I to angiotensin II, thereby reducing blood pressure. The drug is currently approved and in use in several countries, but not available in the United States.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult volunteers after single oral administration.

References

1. Ding, PY, et al., & Liao, W (2000). Does Chinese ethnicity affect the pharmacokinetics and pharmacodynamics of angiotensin-converting enzyme inhibitors?. Journal of human hypertension 14(3) 163–170. DOI:10.1038/sj.jhh.1000856 PUBMED:https://pubmed.ncbi.nlm.nih.gov/10694829

Revisions

• 06/2025 initial generated model