.Pharmacolibrary.Drugs.C_CardiovascularSystem.C09B_AceInhibitorsCombinations.C09BX02_PerindoprilAndBisoprolol.PerindoprilAndBisoprolol .Pharmacolibrary.Drugs.C_CardiovascularSystem.C09B_AceInhibitorsCombinations.C09BX02_PerindoprilAndBisoprolol.PerindoprilAndBisoprolol| name: | PerindoprilAndBisoprolol | |
| ATC code: | C09BX02 | route: | oral |
| compartments: | 1 | |
| dosage: | 5 | mg |
| volume of distribution: | 1 | L |
| clearance: | 20 | L/h |
| other parameters in model implementation | ||
Perindopril and bisoprolol is a fixed-dose combination medication used in the management of hypertension and other cardiovascular indications. Perindopril is an angiotensin-converting enzyme (ACE) inhibitor while bisoprolol is a selective beta-1 blocker. This combination is designed to provide synergistic blood pressure lowering effects and is approved for use today in many countries.
No population pharmacokinetic model published for the fixed-dose combination product C09BX02; below parameters are estimates based on known PK properties of individual components in healthy adults.