.Pharmacolibrary.Drugs.C_CardiovascularSystem.C09D_AngiotensinIiReceptorBlockersArbsCombinations.C09DB05_IrbesartanAndAmlodipine.IrbesartanAndAmlodipine .Pharmacolibrary.Drugs.C_CardiovascularSystem.C09D_AngiotensinIiReceptorBlockersArbsCombinations.C09DB05_IrbesartanAndAmlodipine.IrbesartanAndAmlodipine| name: | IrbesartanAndAmlodipine | |
| ATC code: | C09DB05 | route: | oral |
| compartments: | 2 | |
| dosage: | 150 | mg |
| volume of distribution: | 53 | L |
| clearance: | 3.9 | L/h |
| other parameters in model implementation | ||
Irbesartan and amlodipine is a fixed-dose combination medication used for the treatment of hypertension. Irbesartan is an angiotensin II receptor blocker (ARB), while amlodipine is a calcium channel blocker; together, they lower blood pressure and reduce cardiovascular risk. Both drugs are widely approved and used in clinical practice.
Estimated typical pharmacokinetic parameters for healthy adult subjects after oral administration, based on known individual PK of irbesartan and amlodipine and cross-referenced summary data of combination products.