.Pharmacolibrary.Drugs.C_CardiovascularSystem.C09X_OtherAgentsActingOnTheReninAngiotensinSystem.C09XA01_Remikiren.Remikiren .Pharmacolibrary.Drugs.C_CardiovascularSystem.C09X_OtherAgentsActingOnTheReninAngiotensinSystem.C09XA01_Remikiren.Remikiren| name: | Remikiren |
| ATC code: | C09XA01 | route: | oral |
| n-compartments | 1 |
Remikiren is a renin inhibitor, belonging to the class of antihypertensive agents. It was developed as an orally active, non-peptide inhibitor for the treatment of hypertension. However, it is not currently approved or marketed for medical use.
Pharmacokinetic parameters estimated for healthy adult subjects following oral administration; no published clinical PK model identified.
Weber, C, et al., & Van Brummelen, P (1993). Multiple dose pharmacokinetics and concentration effect relationship of the orally active renin inhibitor remikiren (Ro 42-5892) in hypertensive patients. British journal of clinical pharmacology 36(6) 547–554. DOI:10.1111/j.1365-2125.1993.tb00413.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/12959271