.Pharmacolibrary.Drugs.C_CardiovascularSystem.C10A_LipidModifyingAgentsPlain.C10AA04_Fluvastatin.Fluvastatin

Information

name:Fluvastatin
ATC code:C10AA04
route:oral
n-compartments1

Fluvastatin is an orally administered lipid-lowering agent that belongs to the statin class of drugs. It is primarily used to reduce levels of cholesterol and triglycerides in the blood and is approved for the treatment of hypercholesterolemia and mixed dyslipidemia to prevent cardiovascular disease.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult volunteers after a single oral dose administration.

References

  1. Xu, HR, et al., & Zhu, JR (2012). The difference in pharmacokinetics and pharmacodynamics between extended-release fluvastatin and immediate-release fluvastatin in healthy Chinese subjects. Journal of biomedicine & biotechnology 2012 386230–None. DOI:10.1155/2012/386230 PUBMED:https://pubmed.ncbi.nlm.nih.gov/22811596

  2. Kirchheiner, J, & Brockmöller, J (2005). Clinical consequences of cytochrome P450 2C9 polymorphisms. Clinical pharmacology and therapeutics 77(1) 1–16. DOI:10.1016/j.clpt.2004.08.009 PUBMED:https://pubmed.ncbi.nlm.nih.gov/15637526

  3. Pincus, KJ, & Hynicka, LM (2013). Prophylaxis of thromboembolic events in patients with nephrotic syndrome. The Annals of pharmacotherapy 47(5) 725–734. DOI:10.1345/aph.1R530 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23613095

Revisions


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