.Pharmacolibrary.Drugs.C_CardiovascularSystem.C10A_LipidModifyingAgentsPlain.C10AC04_Colesevelam.Colesevelam .Pharmacolibrary.Drugs.C_CardiovascularSystem.C10A_LipidModifyingAgentsPlain.C10AC04_Colesevelam.Colesevelam| name: | Colesevelam | |
| ATC code: | C10AC04 | route: | oral |
| compartments: | 1 | |
| dosage: | 3750 | mg |
| volume of distribution: | 1 | L |
| clearance: | 0 | L/hr |
| other parameters in model implementation | ||
Colesevelam is a bile acid sequestrant used primarily to lower low-density lipoprotein (LDL) cholesterol in patients with hyperlipidemia and for improving glycemic control in adults with type 2 diabetes mellitus. It is an FDA-approved medication used as an adjunct to diet and exercise.
Pharmacokinetics in healthy adults; colesevelam is a non-absorbed polymer, pharmacokinetic parameters are not applicable as the drug is not systemically absorbed.
Neumiller, JJ, & Setter, SM (2009). Pharmacologic management of the older patient with type 2 diabetes mellitus. The American journal of geriatric pharmacotherapy 7(6) 324–342. DOI:10.1016/j.amjopharm.2009.12.002 PUBMED:https://pubmed.ncbi.nlm.nih.gov/20129254