.Pharmacolibrary.Drugs.C_CardiovascularSystem.C10A_LipidModifyingAgentsPlain.C10AX12_Lomitapide.Lomitapide .Pharmacolibrary.Drugs.C_CardiovascularSystem.C10A_LipidModifyingAgentsPlain.C10AX12_Lomitapide.Lomitapide| name: | Lomitapide | |
| ATC code: | C10AX12 | route: | oral |
| compartments: | 1 | |
| dosage: | 60 | mg |
| volume of distribution: | 985 | L |
| clearance: | 32.5 | L/h |
| other parameters in model implementation | ||
Lomitapide is a microsomal triglyceride transfer protein (MTP) inhibitor used as an adjunct treatment for lowering low-density lipoprotein cholesterol (LDL-C) levels in patients with homozygous familial hypercholesterolemia (HoFH). It is approved for use in adults as an adjunct to other lipid-lowering therapies and dietary modifications.
Pharmacokinetic parameters for lomitapide in healthy adults after oral administration under fasting conditions.