.Pharmacolibrary.Drugs.C_CardiovascularSystem.C10B_LipidModifyingAgentsCombinations.C10BA12_PravastatinEzetimibeAndFenofibra.PravastatinEzetimibeAndFenofibra

Information

name:PravastatinEzetimibeAndFenofibrate
ATC code:C10BA12
route:oral
n-compartments1

Combination product containing pravastatin (an HMG-CoA reductase inhibitor/statin), ezetimibe (a cholesterol absorption inhibitor), and fenofibrate (a fibric acid derivative). Used for the treatment of mixed dyslipidemia and hypercholesterolemia to lower LDL cholesterol, triglycerides, and increase HDL cholesterol. No co-formulated product with all three agents is currently approved; such combinations are sometimes used off-label in clinical practice.

Pharmacokinetics

No pharmacokinetic studies or population PK models identified for the triple fixed-dose combination. Estimates based on individual component data in healthy adults after oral administration.

References

    Revisions


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