.Pharmacolibrary.Drugs.C_CardiovascularSystem.C10B_LipidModifyingAgentsCombinations.C10BX17_RosuvastatinAndRamipril.RosuvastatinAndRamipril .Pharmacolibrary.Drugs.C_CardiovascularSystem.C10B_LipidModifyingAgentsCombinations.C10BX17_RosuvastatinAndRamipril.RosuvastatinAndRamipril| name: | RosuvastatinAndRamipril | |
| ATC code: | C10BX17 | route: | oral |
| compartments: | 1 | |
| dosage: | 10 | mg |
| volume of distribution: | 50 | L |
| clearance: | 20 | l/h |
| other parameters in model implementation | ||
Rosuvastatin and ramipril are used in combination therapy for cardiovascular risk reduction; rosuvastatin is a statin used to lower cholesterol and ramipril is an ACE inhibitor used for hypertension and heart failure. The fixed combination is approved in some countries for patients requiring both treatments.
No published population pharmacokinetic studies or dedicated PK study specific for the fixed-dose combination C10BX17. Estimates are based on the known oral pharmacokinetics of rosuvastatin and ramipril individually in healthy adults.