.Pharmacolibrary.Drugs.C_CardiovascularSystem.C10B_LipidModifyingAgentsCombinations.C10BX18_AtorvastatinAmlodipineAn.AtorvastatinAmlodipineAn .Pharmacolibrary.Drugs.C_CardiovascularSystem.C10B_LipidModifyingAgentsCombinations.C10BX18_AtorvastatinAmlodipineAn.AtorvastatinAmlodipineAn| name: | AtorvastatinAmlodipineAndRamipril | |
| ATC code: | C10BX18 | |
| route: | oral | |
| compartments: | 1 | |
| dosage: | 10 | mg |
| volume of distribution: | 250 | L |
| clearance: | 55 | L/h |
| other parameters in model implementation | ||
A fixed-dose combination of three cardiovascular active agents: atorvastatin (a statin lipid-lowering agent), amlodipine (a calcium channel blocker for hypertension and angina), and ramipril (an ACE inhibitor for hypertension and heart failure). Used for primary or secondary prevention of cardiovascular disease; approved in some countries as a combination product.
Pharmacokinetic parameters estimated based on published data for monocomponents in healthy adults; there are no published population PK studies specifically for the fixed-dose combination with ATC code C10BX18.