.Pharmacolibrary.Drugs.D_Dermatologicals.D01A_AntifungalsForTopicalUse.D01AC15_Fluconazole.Fluconazole_1

Information

name:Fluconazole_1
ATC code:D01AC15_1
route:intravenous
n-compartments1

Fluconazole is a triazole antifungal medication used to treat and prevent a variety of fungal and yeast infections, including candidiasis and cryptococcal meningitis. It is approved for use in many countries and is commonly prescribed both for systemic and superficial mycoses.

Pharmacokinetics

Pharmacokinetic parameters as reported in healthy adult volunteers after single intravenous dose.

References

  1. Tanzawa, A, et al., & Yamatani, A (2022). Fluconazole Population Pharmacokinetics after Fosfluconazole Administration and Dosing Optimization in Extremely Low-Birth-Weight Infants. Microbiology spectrum 10(2) e0195221–None. DOI:10.1128/spectrum.01952-21 PUBMED:https://pubmed.ncbi.nlm.nih.gov/35266811

  2. Wang, H, et al., & Li, X (2024). Population pharmacokinetics of fluconazole for prevention or treatment of invasive candidiasis in Chinese young infants. Naunyn-Schmiedeberg's archives of pharmacology 397(11) 8853–8862. DOI:10.1007/s00210-024-03184-7 PUBMED:https://pubmed.ncbi.nlm.nih.gov/38850301

  3. Momper, JD, et al., & Benjamin, DK (2016). Population Pharmacokinetics of Fluconazole in Premature Infants with Birth Weights Less than 750 Grams. Antimicrobial agents and chemotherapy 60(9) 5539–5545. DOI:10.1128/AAC.00963-16 PUBMED:https://pubmed.ncbi.nlm.nih.gov/27401564

Revisions


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