.Pharmacolibrary.Drugs.D_Dermatologicals.D01A_AntifungalsForTopicalUse.D01AC19_Efinaconazole.Efinaconazole

Information

name:Efinaconazole
ATC code:D01AC19
route:topical
n-compartments1

Efinaconazole is a triazole antifungal agent primarily indicated for the topical treatment of onychomycosis (fungal infection) of the toenails. It is approved for use in various countries and is currently available as a prescription medication.

Pharmacokinetics

Pharmacokinetic parameters estimated for topical application in healthy adult subjects; limited systemic absorption observed after application to the toenails.

References

  1. Eichenfield, LF, et al., & Guenin, E (2020). Safety, Pharmacokinetics, and Efficacy of Efinaconazole 10% Topical Solution for Onychomycosis Treatment in Pediatric Patients. Journal of drugs in dermatology : JDD 19(9) 867–872. DOI:10.36849/JDD.2020.10.36849/JDD.2020.5401 PUBMED:https://pubmed.ncbi.nlm.nih.gov/33026753

  2. Gupta, AK, et al., & Cooper, EA (2024). Efinaconazole 10% solution: a comprehensive review of its use in the treatment of onychomycosis. Expert opinion on pharmacotherapy 25(15) 1983–1998. DOI:10.1080/14656566.2024.2416924 PUBMED:https://pubmed.ncbi.nlm.nih.gov/39394930

  3. Gregoriou, S, et al., & Rigopoulos, D (2022). Novel and Investigational Treatments for Onychomycosis. Journal of fungi (Basel, Switzerland) 8(10) –. DOI:10.3390/jof8101079 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36294644

Revisions


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