.Pharmacolibrary.Drugs.D_Dermatologicals.D01B_AntifungalsForSystemicUse.D01BA02_Terbinafine.Terbinafine

Information

name:Terbinafine
ATC code:D01BA02
route:oral
n-compartments2

Terbinafine is an allylamine antifungal agent primarily used to treat fungal infections of the skin and nails, including onychomycosis and tinea infections. It is approved and widely used today for both oral and topical treatment of dermatophytic infections.

Pharmacokinetics

Pharmacokinetic parameters in healthy adult volunteers (oral administration).

References

  1. Scher, RK (1999). Onychomycosis: therapeutic update. Journal of the American Academy of Dermatology 40(6 Pt 2) S21–S26. DOI:10.1016/s0190-9622(99)70397-x PUBMED:https://pubmed.ncbi.nlm.nih.gov/10367912

  2. Gupta, AK, et al., & Cooper, EA (2003). The efficacy and safety of terbinafine in children. Journal of the European Academy of Dermatology and Venereology : JEADV 17(6) 627–640. DOI:10.1046/j.1468-3083.2003.00691.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/14761128

  3. Gupta, AK, et al., & Cooper, EA (2024). Efinaconazole 10% solution: a comprehensive review of its use in the treatment of onychomycosis. Expert opinion on pharmacotherapy 25(15) 1983–1998. DOI:10.1080/14656566.2024.2416924 PUBMED:https://pubmed.ncbi.nlm.nih.gov/39394930

Revisions


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