.Pharmacolibrary.Drugs.D_Dermatologicals.D02B_ProtectivesAgainstUvRadiation.D02BA02_Octinoxate.Octinoxate .Pharmacolibrary.Drugs.D_Dermatologicals.D02B_ProtectivesAgainstUvRadiation.D02BA02_Octinoxate.Octinoxate| name: | Octinoxate | |
| ATC code: | D02BA02 | route: | topical |
| compartments: | 1 | |
| dosage: | 10 | mg |
| volume of distribution: | 3 | L |
| clearance: | 0.2 | L/h/kg |
| other parameters in model implementation | ||
Octinoxate (octyl methoxycinnamate or ethylhexyl methoxycinnamate) is an organic compound used primarily as a UV-B filter in sunscreens, cosmetics, and skin care products for the prevention of sunburn and photodamage. It is used topically and is approved in many countries for over-the-counter use for skin protection against the harmful effects of solar ultraviolet radiation.
Estimated pharmacokinetic parameters for healthy adults; specific human PK data are lacking in primary literature.
Hayden, CG, et al., & Roberts, MS (2005). Sunscreen penetration of human skin and related keratinocyte toxicity after topical application. Skin pharmacology and physiology 18(4) 170–174. DOI:10.1159/000085861 PUBMED:https://pubmed.ncbi.nlm.nih.gov/15908756