.Pharmacolibrary.Drugs.D_Dermatologicals.D05B_AntipsoriaticsForSystemicUse.D05BA02_Methoxsalen.Methoxsalen .Pharmacolibrary.Drugs.D_Dermatologicals.D05B_AntipsoriaticsForSystemicUse.D05BA02_Methoxsalen.Methoxsalen| name: | Methoxsalen | |
| ATC code: | D05BA02 | route: | oral |
| compartments: | 1 | |
| dosage: | 10 | mg |
| volume of distribution: | 1.5 | L |
| clearance: | 18.1 | L/h |
| other parameters in model implementation | ||
Methoxsalen (also known as 8-methoxypsoralen) is a furocoumarin derivative used primarily in the treatment of psoriasis, vitiligo, and some cutaneous lymphomas as a photosensitizing agent in combination with UVA (PUVA) therapy. It is still approved and used for these indications.
Pharmacokinetic parameters in healthy adult volunteers after oral administration.
Micheal, F, et al., & Motial, BM (2021). Assessment of Prescribability and Switchability by Using Multiple Bioequivalence Assessment Approaches. Drug metabolism letters 14(2) 141–151. DOI:10.2174/1872312814666210319124659 PUBMED:https://pubmed.ncbi.nlm.nih.gov/33745439