.Pharmacolibrary.Drugs.D_Dermatologicals.D05B_AntipsoriaticsForSystemicUse.D05BA03_Bergapten.Bergapten .Pharmacolibrary.Drugs.D_Dermatologicals.D05B_AntipsoriaticsForSystemicUse.D05BA03_Bergapten.Bergapten| name: | Bergapten |
| ATC code: | D05BA03 | route: | oral |
| n-compartments | 1 |
Bergapten (5-methoxypsoralen) is a furocoumarin compound primarily found in bergamot and other citrus oils. Historically, it has been used as a photosensitizing agent in the treatment of skin disorders such as psoriasis and vitiligo in combination with UVA phototherapy (PUVA therapy). It is not widely approved for systemic use as a drug today due to safety concerns, particularly phototoxicity and carcinogenicity risks.
Estimated pharmacokinetic parameters for healthy adults administered bergapten orally. No specific clinical pharmacokinetic data for bergapten as a drug in humans found in published studies.