.Pharmacolibrary.Drugs.D_Dermatologicals.D06B_ChemotherapeuticsForTopicalUse.D06BA01_SilverSulfadiazine.SilverSulfadiazine .Pharmacolibrary.Drugs.D_Dermatologicals.D06B_ChemotherapeuticsForTopicalUse.D06BA01_SilverSulfadiazine.SilverSulfadiazine| name: | SilverSulfadiazine |
| ATC code: | D06BA01 | route: | topical |
| n-compartments | 1 |
Silver sulfadiazine is a topical antimicrobial agent used primarily for the prevention and treatment of wound infections in patients with second- and third-degree burns. The drug acts by releasing silver ions that are bactericidal and by inhibiting bacterial growth. It is generally applied as a cream and is approved and widely used in clinical burn care.
Pharmacokinetic estimates based on available data in adults with burn wounds; limited systemic absorption occurs through damaged skin, with kinetics mostly described for sulfadiazine component as silver is poorly absorbed.