.Pharmacolibrary.Drugs.D_Dermatologicals.D06B_ChemotherapeuticsForTopicalUse.D06BX01_Metronidazole.Metronidazole .Pharmacolibrary.Drugs.D_Dermatologicals.D06B_ChemotherapeuticsForTopicalUse.D06BX01_Metronidazole.Metronidazole| name: | Metronidazole |
| ATC code: | D06BX01 | route: | oral |
| n-compartments | 1 |
Metronidazole is an antibiotic and antiprotozoal medication used primarily to treat infections caused by anaerobic bacteria and certain parasites, such as Giardia and Trichomonas. It is approved and commonly used today for the treatment of bacterial vaginosis, pelvic inflammatory disease, and Clostridioides difficile infection, among others.
Pharmacokinetic parameters reported for healthy adult volunteers after single oral dose administration.
Sullins, AK, & Abdel-Rahman, SM (2013). Pharmacokinetics of antibacterial agents in the CSF of children and adolescents. Paediatric drugs 15(2) 93–117. DOI:10.1007/s40272-013-0017-5 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23529866
Vande Griend, JP, et al., & Linnebur, SA (2012). A year in review: new drugs for older adults in 2011. The American journal of geriatric pharmacotherapy 10(4) 258–263. DOI:10.1016/j.amjopharm.2012.05.003 PUBMED:https://pubmed.ncbi.nlm.nih.gov/22682643
Carlson, TJ, et al., & Garey, KW (2022). Fulminant Clostridioides difficile Infection: A Review of Treatment Options for a Life-Threatening Infection. Seminars in respiratory and critical care medicine 43(1) 28–38. DOI:10.1055/s-0041-1740973 PUBMED:https://pubmed.ncbi.nlm.nih.gov/35172356