.Pharmacolibrary.Drugs.D_Dermatologicals.D06B_ChemotherapeuticsForTopicalUse.D06BX02_IngenolMebutate.IngenolMebutate .Pharmacolibrary.Drugs.D_Dermatologicals.D06B_ChemotherapeuticsForTopicalUse.D06BX02_IngenolMebutate.IngenolMebutate| name: | IngenolMebutate |
| ATC code: | D06BX02 | route: | topical |
| n-compartments | 1 |
Ingenol mebutate is a diterpene ester derived from the plant Euphorbia peplus. It is used topically for the treatment of actinic keratosis, a precancerous skin lesion caused by sun exposure. Due to safety concerns, it has been withdrawn in some regions (e.g., EU) from the market. It is not widely used today.
No conventional systemic pharmacokinetic parameters are available as per published literature, since ingenol mebutate is used topically and exhibits minimal systemic absorption in healthy adult subjects with actinic keratosis.