.Pharmacolibrary.Drugs.D_Dermatologicals.D06B_ChemotherapeuticsForTopicalUse.D06BX03_Tirbanibulin.Tirbanibulin .Pharmacolibrary.Drugs.D_Dermatologicals.D06B_ChemotherapeuticsForTopicalUse.D06BX03_Tirbanibulin.Tirbanibulin| name: | Tirbanibulin | |
| ATC code: | D06BX03 | route: | topical |
| compartments: | 1 | |
| dosage: | 25 | mg |
| volume of distribution: | 1 | L |
| clearance: | 0 | |
| other parameters in model implementation | ||
Tirbanibulin is a topical synthetic inhibitor of tubulin polymerization and Src kinase signaling, used for the treatment of actinic keratosis. It is approved for use in adults as a 1% ointment applied to the affected area of the skin.
Pharmacokinetic parameters estimated for adults receiving topical application of tirbanibulin 1% ointment. No systemic exposure measured in healthy subjects or patients due to extremely low bioavailability.