.Pharmacolibrary.Drugs.D_Dermatologicals.D08A_AntisepticsAndDisinfectants.D08AE01_Hexachlorophene.Hexachlorophene

Information

Hexachlorophene is an organochlorine compound formerly used as a topical anti-infective and disinfectant. It was widely utilized in the 20th century for hand washing in hospitals and as a preservative in soaps and cosmetics. Due to risks of neurotoxicity, especially in neonates, its use is now highly restricted or banned in most countries, with very limited approved medical uses.

Pharmacokinetics

No specific pharmacokinetic data are available in the published literature for humans; estimates are provided based on limited data from animal studies and case reports.

References

1. Mancini, AJ (2004). Skin. Pediatrics 113(4 Suppl) 1114–1119. PUBMED:https://pubmed.ncbi.nlm.nih.gov/15060207

Revisions

• 06/2025 initial generated model