.Pharmacolibrary.Drugs.D_Dermatologicals.D08A_AntisepticsAndDisinfectants.D08AG01_IodineOctylphenoxypolygl.IodineOctylphenoxypolygl

Information

name:IodineOctylphenoxypolyglycolether
ATC code:D08AG01
route:topical
n-compartments1

Iodine/octylphenoxypolyglycolether (also known as 'povidone-iodine' or 'non-ionic iodophor') is a topical antiseptic solution used for skin disinfection before and after surgery, and for cleansing wounds. It is a complex of iodine with a surfactant (octylphenoxypolyglycolether) to provide sustained iodine release and increased solubility. This formulation is approved and commonly used today for antimicrobial purposes on skin and mucous membranes.

Pharmacokinetics

No published primary pharmacokinetic studies were found specifically for iodine/octylphenoxypolyglycolether in humans (all sexes, all ages, topical use for disinfection). Since the product is intended for local, external use, systemic absorption is considered minimal in healthy, unbroken skin.

References

  1. Mancini, AJ (2004). Skin. Pediatrics 113(4 Suppl) 1114–1119. PUBMED:https://pubmed.ncbi.nlm.nih.gov/15060207

  2. Lin, YS, et al., & Milgrom, P (2018). Pharmacokinetics of Iodine and Fluoride following Application of an Anticaries Varnish in Adults. JDR clinical and translational research 3(3) 238–245. DOI:10.1177/2380084418771930 PUBMED:https://pubmed.ncbi.nlm.nih.gov/30938600

  3. Below, H, et al., & Rudolph, P (2006). Systemic iodine absorption after preoperative antisepsis using povidone-iodine in cataract surgery-- an open controlled study. Dermatology (Basel, Switzerland) 212 Suppl 1 41–46. DOI:10.1159/000089198 PUBMED:https://pubmed.ncbi.nlm.nih.gov/16490974

Revisions


Generated at 2025-07-21T18:21:10Z by OpenModelicaOpenModelica 1.25.1 using GenerateDoc.mos