.Pharmacolibrary.Drugs.D_Dermatologicals.D08A_AntisepticsAndDisinfectants.D08AL01_SilverNitrate.SilverNitrate

Information

name:SilverNitrate
ATC code:D08AL01
route:
n-compartments1

Silver nitrate is an inorganic compound formerly used as a topical antiseptic and for cauterization of wounds. Historically, it has been used to prevent ophthalmia neonatorum (eye infection in newborns). Due to toxicity and the emergence of more specific agents, it is rarely used today and has limited applications in clinical medicine.

Pharmacokinetics

No pharmacokinetic data regarding absorption, distribution, metabolism, or excretion of silver nitrate in humans is available in the published literature. Due to its highly reactive ionic nature and local mechanism of action, systemic pharmacokinetics are generally not relevant. Any attempt at compartmental modeling or parameter estimation is speculative.

References

  1. Nguyen, RC, et al., & LeBlanc, A (1999). Argyremia in septal cauterization with silver nitrate. The Journal of otolaryngology 28(4) 211–216. PUBMED:https://pubmed.ncbi.nlm.nih.gov/10461258

  2. Kumari, N, et al., & Jagadevan, S (2019). Arsenite biotransformation by Rhodococcus sp.: Characterization, optimization using response surface methodology and mechanistic studies. The Science of the total environment 687 577–589. DOI:10.1016/j.scitotenv.2019.06.077 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31216511

  3. Fernández, A, et al., & Lloret, E (2010). Cellulose-silver nanoparticle hybrid materials to control spoilage-related microflora in absorbent pads located in trays of fresh-cut melon. International journal of food microbiology 142(1-2) 222–228. DOI:10.1016/j.ijfoodmicro.2010.07.001 PUBMED:https://pubmed.ncbi.nlm.nih.gov/20656367

Revisions


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