.Pharmacolibrary.Drugs.D_Dermatologicals.D10A_AntiAcnePreparationsForTopicalUse.D10AD03_Adapalene.Adapalene .Pharmacolibrary.Drugs.D_Dermatologicals.D10A_AntiAcnePreparationsForTopicalUse.D10AD03_Adapalene.Adapalene| name: | Adapalene | |
| ATC code: | D10AD03 | route: | topical |
| compartments: | 1 | |
| dosage: | 2 | mg |
| volume of distribution: | 13.1 | L |
| clearance: | 0.45 | L/h/kg |
| other parameters in model implementation | ||
Adapalene is a third-generation topical retinoid primarily used for the treatment of acne vulgaris. It acts as a modulator of cellular differentiation, keratinization, and inflammatory processes. Adapalene is approved for use in many countries as a prescription and recently as an over-the-counter medication.
Pharmacokinetic parameters reported for topical adapalene in healthy adult volunteers.
Kumar, V, & Banga, AK (2016). Intradermal and follicular delivery of adapalene liposomes. Drug development and industrial pharmacy 42(6) 871–879. DOI:10.3109/03639045.2015.1082580 PUBMED:https://pubmed.ncbi.nlm.nih.gov/27031916