.Pharmacolibrary.Drugs.D_Dermatologicals.D10A_AntiAcnePreparationsForTopicalUse.D10AD53_AdapaleneCombinations.AdapaleneCombinations .Pharmacolibrary.Drugs.D_Dermatologicals.D10A_AntiAcnePreparationsForTopicalUse.D10AD53_AdapaleneCombinations.AdapaleneCombinations| name: | AdapaleneCombinations |
| ATC code: | D10AD53 | route: | topical |
| n-compartments | 1 |
Adapalene, in combination with benzoyl peroxide (as in ATC code D10AD53), is a topical retinoid used primarily for the treatment of acne vulgaris. The combination enhances comedolytic, anti-inflammatory, and antibacterial effects. This product is approved for clinical use in several countries.
Estimated pharmacokinetic model for healthy adults using topical gel formulation of adapalene 0.1% with benzoyl peroxide 2.5%; limited systemic absorption expected in healthy skin.