.Pharmacolibrary.Drugs.D_Dermatologicals.D10B_AntiAcnePreparationsForSystemicUse.D10BA01_Isotretinoin.Isotretinoin .Pharmacolibrary.Drugs.D_Dermatologicals.D10B_AntiAcnePreparationsForSystemicUse.D10BA01_Isotretinoin.Isotretinoin| name: | Isotretinoin |
| ATC code: | D10BA01 | route: | oral |
| n-compartments | 1 |
Isotretinoin is a retinoid derivative (13-cis-retinoic acid) used primarily in the treatment of severe recalcitrant nodular acne. It is also occasionally used for other keratinization disorders. Isotretinoin is an oral drug approved by regulatory authorities such as the FDA.
Pharmacokinetic parameters in healthy adult volunteers under fasting conditions (single oral dose administration).
Stotland, M, et al., & Kissling, RF (2009). Dapsone 5% gel: a review of its efficacy and safety in the treatment of acne vulgaris. American journal of clinical dermatology 10(4) 221–227. DOI:10.2165/00128071-200910040-00002 PUBMED:https://pubmed.ncbi.nlm.nih.gov/19489655